Dyshidrotic Eczema

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What is Dyshidrotic Eczema?

  • A skin condition that causes itchy, fluid-filled bumps on the palms of the hands and soles of the feet

  • This is also known as acute palmoplantar eczema or pompholyx.

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What causes Dyshidrotic Eczema?

  • The cause is not completely known.

  • Dry skin and irritants, such as harsh chemicals, make the symptoms worse.

  • One theory is that a problem with proteins in the skin leads to water loss from the skin layers.

What are the symptoms of Dyshidrotic Eczema?

  • Itchy, fluid-filled bumps on the palms of the hands and soles of the feet

How is Dyshidrotic Eczema diagnosed?

  • In most cases, primary care providers diagnose dyshidrotic eczema by carefully examining the skin, especially the hands and feet.

  • In some cases, the diagnosis may be made by a specialist, such as a specialist in skin conditions (dermatologist) or a specialist in allergic conditions (allergist).

How can I prevent Dyshidrotic Eczema?

  • Use lukewarm (not hot) water when washing hands.

  • Dry hands well after washing.

  • Immediately after drying hands, apply moisturizer.

  • Wear gloves when outside in cold weather, and when working in water.

  • Avoid direct skin contact with irritants, such as harsh chemicals, hair dyes, and acidic foods like citrus fruit.

How is this treated?

  • Moisturize affected areas frequently throughout the day.

  • Your clinician may prescribe topical treatments, such as creams or ointments.

When to call your healthcare team:

  • The rash is not improving with the treatment plan.

  • Your child is getting worse

  • You have other questions or concerns

This publication was adapted from information from UpToDate (“Acute palmoplantar eczema (dyshidrotic eczema)”). Authors: Denis Sasseville, MD, FRCPC, Marie-Claude Houle, MDCM. June 2024.

Reviewed by: JW, MD, Patient Education Committee | 06/2025