Dosing Charts for Antihistamines

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Appointment Info Care Decision Info

DISCLAIMER: This material is for educational purposes only. You, the reader, assume full responsibility for how you choose to use it. It is not intended to provide medical advice, diagnosis, or treatment, nor does it replace the advice or counsel of a doctor or health care professional. Reference to a specific commercial product, service, or external web site does not imply endorsement or recommendation of that product, service, or external web site content by CPCMG. We attempt to keep lists of resources and referrals as up to date as possible; however, this information is constantly changing. Please check with the service provider and your insurance company to verify coverage.

Cetirizine (Zyrtec)

Child's age

6 months-less than 2 years

2-6 years

6-12 years

> 12 years

Total Amount (mg)

Please ask CPCMG triage nurse or healthcare provider

2.5-5 mg

5-10 mg

10 mg

Liquid 5mg/5ml

2.5-5 mL

5-10 mL

10 mL

Chewable 5 mg

1 tablet

1-2 tablets

2 tablets

Tablet 10 mg

1 tablet

1 tablet

Uses: Antihistamine for the treatment of allergic reactions, nasal allergies, hives and itching. Give once daily as needed.

NOTES:
1) Dosing is based on AGE, not weight.
2) Consult a healthcare provider for children less than 2 years.
3) WARNING: Be aware that many OTC medications such as cold preparations may contain other antihistamines, which can lead to double dosing. Read all OTC labels carefully. The FDA advises against using multi-ingredient OTC medications in children less than 6 years of age.

Loratadine (Claritin)

Child's age

2-6 years

6-12 years

> 12 years

Total Amount (mg)

5 mg

10 mg

10 mg

Liquid 5mg/5ml

5 mL

10 mL

10 mL

Chewable 5 mg

1 tablet

2 tablets

2 tablets

Redi-tabs 10 mg

1 tablet

1 tablet

Tablet 10 mg

1 tablet

1 tablet

Uses: Antihistamine for the treatment of allergic reactions, nasal allergies, hives and itching. Give once daily as needed.

NOTES:
1) Dosing is based on AGE, not weight.
2) Consult a healthcare provider for children less than 2 years.
3) WARNING: Be aware that many OTC medications such as cold preparations may contain other antihistamines, which can lead to double dosing. Read all OTC labels carefully. The FDA advises against using multi-ingredient OTC medications in children less than 6 years of age.

Diphenhydramine (Benadryl)

Child's weight is more than (LBS)

20 pounds

25 pounds

38 pounds

50 pounds

100 pounds

Total Amount (mg)

10 mg

12.5 mg

19 mg

25 mg

25-50 mg

Liquid 12.5mg/5ml

3.75 mL

5 mL

7.5 mL

10 mL

Chewable 12.5 mg

1 tablet

1 ½ tablets

2 tablets

2-4 tablets

Capsules 25 mg

1 capsule

2 capsules

Uses: Antihistamine for the treatment of allergic reactions, nasal allergies, hives and itching. Give every 6-8 hours as needed.

NOTES:
1) Dosing is based on WEIGHT, not age. Keep note of your child's most recent weight.
2) Adult dose may be 25 or 50 mg because of sedating effects. Start with 25 mg for children >100 pounds.
3) Consult a healthcare provider for infants <12 months of age due to sedating effects.
4) Benadryl Children's FastMelts: each contains the equivalent of 12.5 mg of diphenhydramine and is dosed like the chewable tablet.
5) WARNING: Be aware that many OTC medications such as cold preparations may contain diphenhydramine, which can lead to double dosing. Read all OTC labels carefully. The FDA advises against using multi-ingredient OTC medications in children less than 6 years of age.

📚 References

This content was adapted from https://www.stanfordchildrens.org/en/services/pediatrics-general/dosage-charts.html.

Reviewed by JW MD, Patient Education Committee.