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Definition
Perioral dermatitis is a common non-contagious rash around the mouth, nose and eyes.
It is also known as periorificial dermatitis.
Image from DermNet - Periorificial dermatitis in children
Image from The Full Spectrum of Dermatology: A Diverse and Inclusive Atlas - Periorificial Dermatitis
Symptoms of Perioral Dermatitis
Small red or pink bumps around your mouth, nose, and sometimes eyes.
Bumps may look like tiny pimples
May have a scaly appearance
What Causes Perioral Dermatitis
The exact cause of perioral dermatitis is not fully understood, but several factors can trigger or worsen it:
Steroid creams: Using steroid creams or ointments on your face is one of the most common triggers. Even over-the-counter hydrocortisone cream can cause this problem.
Skincare products: Heavy moisturizers, thick sunscreens, makeup, and facial creams may contribute to the condition.
Other factors: Fluorinated toothpaste, hormonal changes, and certain medications have also been linked to perioral dermatitis.
How is Perioral Dermatitis Treated?
First step - Stop the triggers:
If you're using any steroid creams on your face, your doctor will help you stop them gradually
Simplify your skincare routine - use only gentle, fragrance-free cleansers and moisturizers.
Avoid heavy makeup and thick facial products.
Prescription treatments: Your doctor may prescribe one or more of the following:
Topical antibiotics: Creams or gels containing metronidazole or erythromycin applied to the affected areas
Oral antibiotics: Pills such as doxycycline, minocycline, or tetracycline for more stubborn cases (note: tetracycline antibiotics should not be used in children under 8 years old or during pregnancy)
Other topical medications: Azelaic acid, pimecrolimus cream, or calcineurin inhibitors may be options, especially for children. Your healthcare provider can discuss options with you.
In some cases, your healthcare provider may recommend referral to a dermatologist.
How Can I Prevent it From Coming Back
Avoid steroid creams on your face: This is the most important step. Never use steroid creams on your face unless specifically prescribed by your doctor for a different condition.
Keep your skincare simple
Use gentle, fragrance-free cleansers.
Choose lightweight, non-comedogenic moisturizers. “Non-comedogenic” means that the product does not clog pores.
Avoid thick, heavy creams and ointments on your face.
Be mindful of other products.
Choose mineral-based sunscreens rather than chemical sunscreens when possible. Mineral-based sunscreens often contain titanium or zinc oxide.
Consider switching to a non-fluorinated toothpaste if your healthcare provider recommends it.
Remove makeup thoroughly each night.
Watch for early signs: If you notice bumps returning, contact your healthcare provider promptly. Early treatment can prevent a full flare-up.
When Should I Call My Healthcare Provider?
Contact your healthcare provider if:
Your rash is not improving after 4-6 weeks of treatment
The rash is spreading or getting worse
You develop severe burning, itching, or pain
You have concerns about your medications or treatment plan
Written by SC, MD, Reviewed by JW MD, Patient Education Committee, 4/2026